Dylan Kosma

Photo of Dylan Kosma, Extension

Dylan Kosma

Associate Professor

Summary

The aerial organs of all higher plants are covered with a lipid-rich cuticle that serves to protect plants from their environment. The cuticle is comprised of a lipid polymer, cutin, that is embedded and covered with aliphatic waxes. Suberin is a biosynthetically-related lipid polymer that is found in tree bark, seed coats, the surface of mature roots and surrounding the vasculature of young roots. Suberin production is a ubiquitous response to wounding.  Collectively, cutin and suberin comprise the most abundant, naturally occurring lipid polymers on the planet. It is estimated that leaf cuticles alone represent a surface area twice that of the earth's land surface.

The Kosma lab is focused on understanding the complex plant lipid polymers cutin and suberin. We use a multidisciplinary approach combining biochemistry, analytical techniques and molecular genetics to comprehend the macromolecular structure and functional significance of these polymers with an emphasis on their role in plant tolerance to abiotic stress.

Education

B.A. Southern Illinois University, 2002
M.S. Southern Illinois University, 2005
Ph.D. Purdue University, 2009

News & Journal Articles, Fact Sheets, Reports...

Book Chapter(s)
Eco-physiological and molecular-genetic determinants of plant cuticle function in drought and salt stress tolerance Dylan K Kosma, Matthew A Jenks 2007, Advances in Molecular breeding toward drought and salt tolerant crops, 91-120
Journals
Physiological characterization of the tomato cutin mutant cd1 under salinity and nitrogen stress
We identified tomato leaf cuticle and root suberin monomers that play a role in the response to nitrogen deficiency and salinity stress and discuss their potential agronomic value for breeding.
Maria-Sole Bonarota, Dylan Kosma & Felipe H. Barrios-Masias 2024, Planta
Mechanisms of Spirodela polyrhiza tolerance to FGD wastewater-induced heavy-metal stress: Lipidomics, transcriptomics, and functional validation
In this study, the response of duckweed (Spirodela polyrhiza) to FGD wastewater–induced heavy metals were systematically analyzed to reveal the heavy metal–tolerance mechanism. These results provide a basis for safe crop production in heavy metal–contaminated soil or water.
Muthan, B., Wang, J., Welti, R., Kosma, D., Yu, L., Deo, B., Khatiwada, S., Vulavala, Childs, K., Xu, C., Durrett, T., Sanjaya, S. 2024, Journal of Hazardous Materials
Structural diversity, biosynthesis, and function of plant falcarin-type polyacetylenic lipids Santos, P., Busta, L., Yim, W. C., Cahoon, E., Kosma, D. 2022, Journal of Experimental Botany, Vol. 73, No. 9 pp. 2889–2904
Chromosomal features of the B. carinata Gomenzer genome assembly
The final piece of the Triangle of U: Evolution of the tetraploid Brassica carinata genome
Here, we report a chromosome scale 1.31-Gbp genome assembly with 156.9-fold sequencing coverage for B. carinata, completing the reference genomes comprising the classic Triangle of U, a classical theory of the evolutionary relationships among these six species.
Won Cheol Yim, Mia L Swain, Dongna Ma, Hong An, Kevin A Bird, David D Curdie, Samuel Wang, Hyun Don Ham, Agusto Luzuriaga-Neira, Jay S Kirkwood, Manhoi Hur, Juan K Q Solomon, Jeffrey F Harper, Dylan K Kosma, David Alvarez-Ponce, John C Cushman, Patrick P Edger, Annaliese S Mason, J Chris Pires, Haibao Tang, Xingtan Zhang 2022, The Plant Cell, Volume 34, Issue 11, November 2022, Pages 4143–4172
A co-opted steroid synthesis gene, maintained in sorghum but not maize, is associated with a divergence in leaf wax chemistry. Busta, L., Schmitz, E., Kosma, D. K., Schnable, J. C., & Cahoon, E. B. 2021, PNAS March 23, 2021 118 (12) e2022982118
Extracellular lipids of Camelina sativa: Characterization of cutin and suberin reveals typical polyester monomers and unusual dicarboxylic fatty acids FM Razeq, DK Kosma, D França, O Rowland, I Molina 2021, Phytochemistry, Volume 184, April 2021, 112665
Transcriptional regulation of wound suberin deposition in potato cultivars with differential wound healing capacity. Z. Wahrenburg, E. Benesch, C. Lowe, J. Jimenez, V. K. R. V., S. Lü, R. Hammerschmidt, D. Douches, W. C. Yim, P. Santos, D. K. Kosma 2021, The Plant Journal, 107(1), 77–99
Isomerization of trans-3-methylglutaconic acid Dylan E. Jones, J. David Ricker, Laina M. Geary, Dylan K. Kosma, Robert O. Ryan 2020, JIMD Reports. 2020;1-9
Extracellular lipids of Camelina sativa: Characterization of cutin and suberin reveals typical polyester monomers and novel functionalized dicarboxylic fatty acids FM Razeq, DK Kosma, O Rowland, I Molina 2020, bioRxiv, 2020
Characterization of Seed, Oil, and Fatty Acid Methyl Esters of an Ethyl Methanesulfonate Mutant of Camelina sativa with Reduced Seed-Coat Mucilage RH Lohaus, JJ Zager, DK Kosma, JC Cushman 2020, Journal of the American Oil Chemists' Society, vol 97, iss 2
Identification of Genes Encoding Enzymes Catalyzing the Early Steps of Carrot Polyacetylene Biosynthesis Busta L, Yim WC, LaBrant EW, Wang P, Grimes L, Malyszka K, Cushman JC, Santos P, Kosma DK, Cahoon EB 2018, Plant Physiology December 2018
Occurrence and Biosynthesis of Alkyl Hydroxycinnamates in Plant Lipid Barriers. Domergue, F., Kosma, D. 2017, Plants, 6(3), 25.
Leaf surface wax composition of genetically diverse mulberry (Morus sp.) genotypes and its close association with expression of genes involved in wax metabolism. Mamrutha, H. M., Nataraja, K. N., Rama, N., Kosma, D., Mogili, T., Jhansi Lakshmi, K., Udaya Kumar, M., Jenks, M. 2017, Current Science, 112(4), 759-766.
The Acyl Desaturase CER17 Is Involved in Producing Wax Unsaturated Primary Alcohols and Cutin Monomers. Yang, X., Zhao, H., Kosma, D., Tomasi, P., Dyer, J. M., Li, R., Wang, Z., Parsons, E. P., Jenks, M., Lu, S. 2017, Plant Physiology, 173, 1109-1124.
Primary fatty alcohols are major components of suberized root tissues of Arabidopsis in the form of alkyl hydroxycinnamates. Delude C., Fouillen L., Bhar P., Cardinal M-J., Pascal S., Santos P., Kosma D.K., Joubès J., Rowland O., Domergue F. 2016, Plant Physiology, 171, 1934-1950
Analysis of aliphatic waxes associated with root periderm or exodermis from eleven plant species. Kosma D.K., Rice A, Pollard M. 2016, Phytochemistry 117: 351–362
Answering a four decade-old question on epicuticular wax biosynthesis. Kosma D.K., Rowland O. 2016, J Exp Bot 67: 2538–2540
Role of HXXXD-motif/BAHD acyltransferases in the biosynthesis of extracellular lipids Isabel Molina & Dylan K Kosma 2015, Plant Cell Reports DOI 10.1007/s00299-014-1721-5
Field production, purification and analysis of high-oleic acetyl-triacylglycerols from transgenic Camelina sativa Jinjie Liu, Henrik Tjellström, Kathleen McGlew, Vincent Shaw, Adam Rice, Jeffrey Simpson, Dylan Kosma, Wei Ma, Weili Yang, Merissa Strawsine, Edgar Cahoon, Timothy P. Durrett, John Ohlrogge 2015, Industrial Crops and Products 65: 259-268
GC-MS-Based Analysis of Chloroform Extracted Suberin-Associated Root Waxes from Arabidopsis and Other Plant Species. Kosma, D., Molina, I., Rowland, O. 2015, Bio-protocol, 5(24), e1679
AtMYB41 activates ectopic suberin synthesis and assembly in multiple plant species and cell types Dylan K Kosma, Jhadeswar Murmu, Fakhria M Razeq, Patricia Santos, Richard Bourgault, Isabel Molina, Owen Rowland 2014, The Plant Journal 80 (2): 216–229
Extracellular lipids of Camelina sativa: Characterization of chloroform-extractable waxes from aerial and subterranean surfaces Fakhria M Razeq, Dylan K Kosma, Owen Rowland, Isabel Molina 2014, Phytochemistry 106:188-196
Altered lipid composition and enhanced nutritional value of Arabidopsis leaves following introduction of an algal diacylglycerol acyltransferase 2 Rachel Miller, Timothy P Durrett, Dylan K Kosma, Todd A Lydic, Bagyalakshmi Muthan, Abraham JK Koo, Yury V Bukhman, Gavin E Reid, Gregg A Howe, John Ohlrogge, Christoph Benning 2013, Plant Cell 25(2):677-693
Suberin- fatty alcohols in Arabidopsis thaliana: Distributions in roots and contributions to seed coat barrier properties. Vishwanath SJ, Kosma DK, Pulsifer IP, Scandola S, Pascal S, Joub Domergue F, Lessire R, Rowland O, Domergue F 2013, Plant Physiology 163:1118-1132.
Identification of an Arabidopsis fatty alcohol: caffeoyl-coenzyme A acyltransferase required for the synthesis of alkyl hydroxycinnamates in root waxes. Kosma DK, Molina I, Ohlrogge JB, and Pollard M 2012, Plant Physiology 160:237-248.
Pleiotropic phenotypes of the sticky peel mutant provide new insight into the role of CUTIN DEFICIENT2 in epidermal cell function in tomato Satya Swathi Nadakuduti, Mike Pollard, Dylan K Kosma, Charles Allen, John B Ohlrogge, Cornelius S Barry 2012, Plant Physiology 159 (3):945-960
The glossyhead1 (gsd1) allele of ACC1 reveals a principal role for multi-domain Acetyl-CoA Carboxylase in the biosynthesis of cuticular waxes by Arabidopsis thaliana. Lü S, Zhao H, Parsons EP, Xu C, Kosma DK, Xu X, Chao D, Lohrey GT, Bangarusamy DK, Wang G, Bressan RA, Jenks MA 2011, Plant Physiology 157:1079-1092.
Fruit cuticle lipid composition during development in tomato ripening mutants DK Kosma, EP Parsons, T Isaacson, S Lü, JKC Rose, MA Jenks 2010, Physiologia Plantarum 139 (1): 107-117
Leaf cuticular wax amount and crystal morphology regulate post-harvest water loss in mulberry (Morus species) HM Mamrutha, T Mogili, K Jhansi Lakshmi, N Rama, Dylan Kosma, M Udaya Kumar, Matthew A Jenks, Karaba N Nataraja 2010, Plant Physiology and Biochemistry 48 (8): 690-696
Changes in properties of wheat leaf cuticle during interactions with Hessian fly. Kosma DK, Nemacheck JA, Jenks MA, Williams CE 2010, The Plant Journal 63:31-43.
Nitrogen supply and cyanide concentration influence the enrichment of nitrogen from cyanide in wheat (Triticum aestivum L.) and sorghum (Sorghum bicolor L.) Stephen D Ebbs, Dylan K Kosma, Elizabeth H Nielson, Marylou Machingura, Alan JM Baker, Ian E Woodrow 2010, Plant, Cell & Environment 33 (7): 1152-1160
Arabidopsis CER8 encodes LONG-CHAIN ACYL-COA SYNTHETASE 1 (LACS1) that has overlapping functions with LACS2 in plant wax and cutin synthesis Arabidopsis CER8 encodes LONG-CHAIN ACYL-COA SYNTHETASE 1 (LACS1) that has overlapping functions with LACS2 in plant wax and cutin synthesis 2009, The Plant Journal 59 (4): 553-564
The impact of water deficiency on leaf cuticle lipids of Arabidopsis Dylan K Kosma, Brice Bourdenx, Amélie Bernard, Eugene P Parsons, Shiyou Lü, Jérôme Joubès, Matthew A Jenks 2009, Plant physiology 151 (4): 1918-1929
The Arabidopsis RESURRECTION1 gene regulates a novel antagonistic interaction in plant defense to biotrophs and necrotrophs Hyung Gon Mang, Kristin A Laluk, Eugene P Parsons, Dylan K Kosma, Bruce R Cooper, Hyeong Cheol Park, Synan AbuQamar, Claudia Boccongelli, Saori Miyazaki, Federica Consiglio, Gabriele Chilosi, Hans J Bohnert, Ray A Bressan, Tesfaye Mengiste, Matthew A Jenks 2009, Plant physiology 151 (1): 290-305
Cutin deficiency in the tomato fruit cuticle consistently affects resistance to microbial infection and biomechanical properties, but not transpirational water loss Tal Isaacson, Dylan K Kosma, Antonio J Matas, Gregory J Buda, Yonghua He, Bingwu Yu, Arika Pravitasari, James D Batteas, Ruth E Stark, Matthew A Jenks, Jocelyn KC Rose 2009, The Plant Journal 60 (2): 363-377
Cadmium bioaccumulation in yellow foxtail (Setaria glauca LP Beauv): Impact on seed head morphology DK Kosma, JA Long, SD Ebbs 2004, American Journal of Undergraduate Research 3 (1): 9-14
Transport and metabolism of free cyanide and iron cyanide complexes by willow S Ebbs, J Bushey, S Poston, D Kosma, M Samiotakis, D Dzombak 2003, Plant, Cell & Environment 26 (9): 1467-1478
Reviews
Functional Role of Long Chain Acyl-CoA Synthetases (LACS) in Plant Development and Stress Responses H Zhao, D Kosma, S Lu 2021, Frontiers in Plant Science, 2021